Code seems to stop xml layout from showing in Android Studio

The problem is that I have an Android app that doesn't seem to show the xml layout when I put this while loop into the class file. The loop is as follows:

while(!clicked){
        button_a.setOnClickListener(new View.OnClickListener() {
            @Override
            public void onClick(View v) {
                player= MediaPlayer.create(GameActivity.this, R.raw.a);
                player.start();
                clicked = true;
                letterTapped = 0;

            }
        });
    }

The whole project works completely fine without it so I'm pretty sure that there must be something wrong with the loop that I am overlooking. If you want me to put any other bits of code up here I will be more than happy to.